Kos is definitely the liveliest island of the Dodecanese, proposing a wide plethora of nightclubs and bars for all musical tastes. The nightlife of Kos is concentrated in two famous streets, the so called bar mile of Kos are Nafklirou and Diakonou streets, just next to the archaeological site, right at the center of the capital. The streets are lined with the best bars and clubs you can find in town and wild parties take place almost every night. Whether you like electronic music, rock sounds, jazz and blues or modern pop, you will find the place for you. There are also many restaurants and taverns where you can have fun or dine. Several of them stay open until early hours! In Kos town there are also several nightclubs scattered throughout the city. The main road and at the beach side in the area of Lambi, and the main road from Kanari street until the port of Kos, an area that stretches for almost 2 miles, is probably the most important.

Far from the city center, there is the resort of Kardamena, which is mostly frequented by British tourists. Many all-night clubs are also found there. Tigaki, Agios Stefanos, Psalidi and Lambi also have few bars and clubs to enjoy a drink.