By Air

San Pablo airport is 7.5 miles north-east of Seville. Flights arrive at Seville from various European cities, including Madrid, Barcelona and other Spanish airports; London Heathrow, Stansted and Gatwick; Bristol, Liverpool, Bristol, Dublin; Frankfurt, Paris, Brussels, Amsterdam, Rome and Milan.

If you want to drive around Andalusia, flying to Málaga may be a good option, although it is around 125 miles away from Seville, Málaga airport is connected to more European cities and flights might be cheaper.

Taxi from Seville airport to city center
The fare for taxis to/from the airport (Tarifa 3): 25 euro (for guidance only)
The fare for taxis to/from the airport at weekends, night time (9pm-7am) and public holidays (includes Semana Santa, Feria, Christmas Eve and New Year`s Eve): 30 euro (for guidance only)
Surcharge for luggage: 0.50 euro per piece
Special night surcharge for Semana Santa and Feria, 9pm-7am: 25%

Bus from airport to city center
The EA airport bus leaves every 15 to 30 minutes (depending on time of day) from 05:45am to 00:45am ( 06:45am to 11:45pm on weekends and holidays), and takes 20-30 minutes. It stops at Santa Justa train station, Ayre Hotel, Hotel Los Lebreros, Nervion Plaza and Hotel Viapol, and terminates in Avenida del Cid, next to the Prado de San Sebastian Metro and tram stop.
It costs 4 euros. (for guidance only)

By Train

Seville's main train station is Santa Justa, located to the north of the city center on Avenida Kansas City. It has shops, restaurants and bars, several car parks, rent a car offices, a taxi rank and bus stop. It is the third busiest station in Spain, by passenger numbers.

One of the fastest and most comfortable ways to arrive in Seville is onthe AVE, the high-speed long-distance train which has services arrivingfrom Madrid, Barcelona, Malaga and Cordoba throughout the day. Thereare also trains arriving at Santa Justa from all over Andalucía, fromthe Cercanias (small local trains) which serve the hill-towns of theSierra Norte, to long-distance trains from Jaen, Granada and Almeria,as well as medium-distance trains with spectacular routes such as theRonda/El Chorro line.
From the train station, you can take a bus or taxi into the city center.

By Bus

In Spain bus and coach services are usually quite efficient and cheap. There are two bus stations in Seville, El Prado and Plaza de Armas connected to most cities in and out Andalucia.