Self-driving offers flexibility and allows you to explore at your own pace. Make sure to rent a suitable vehicle, preferably a 4x4 if you plan to venture into more remote areas or tackle sandy terrain. The park has main gravel roads that connect the major attractions such as Sossusvlei, Deadvlei, and Sesriem Canyon. These roads are generally well-maintained and suitable for regular vehicles. A 4x4 is not necessary for crossing the park on C-roads but is more comfortable and safer to drive in. To drive on some of the D-roads in a sedan you need strong nerves. Expect sandy patches, river crossings without bridges, steep ascents and descents, closed farm gates, etc. For "roads" without official designation you'll need an all-terrain vehicle.

Before setting out, take a map of the park to familiarize yourself with the roads, attractions, and points of interest. Maps are usually available at the park entrance or at the visitor centers.

Ensure you have enough fuel for your journey, as gas stations are limited within the park.